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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN TANKYRASE 2 CATALYTIC DOMAIN IN COMPLEX WITH OLAPARIB
DATE LAST MODIFIED
29 Jan 2020
RELEASE
25 Jan 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
43.61
PUBMED ID
DOI
10.1021/JM201510P

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9H2K2 TNKS2, PARP5B, TANK2, TNKL ESCHERICHIA COLI HUMAN TANK2, POLY [ADP-RIBOSE] POLYMERASE 5B, TNKS-2, TRF1-INTERACTING ANKYRIN-RELATED ADP-RIBOSE POLYMERASE 2, TANKYRASE II,TANKYRASE-LIKE PROTEIN, TANKYRASE-RELATED PROTEIN HUMAN
TANK2, POLY [ADP-RIBOSE] POLYMERASE 5B, TNKS-2, TR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402