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GENERAL
TITLE
DISCOVERY OF POTENT AND SELECTIVE COVALENT INHIBITORS OF JNK
DATE LAST MODIFIED
25 Jul 2012
RELEASE
1 Feb 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.97
RESOLUTION RANGE LOW
156.26
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2011.11.010
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P53779 MAPK10, JNK3, JNK3A, PRKM10, SAPK1B ESCHERICHIA COLI HUMAN MAP KINASE 10, MAPK 10, MAP KINASE P49 3F12, STRESS-ACTIVATED PROTEIN KINASE 1B, SAPK1B, STRESS-ACTIVATED PROTEIN KINASEJNK3, C-JUN N-TERMINAL KINASE 3 HUMAN
MAP KINASE 10, MAPK 10, MAP KINASE P49 3F12, STRES ...
Mutations
P53779 MAPK10, JNK3, JNK3A, PRKM10, SAPK1B ESCHERICHIA COLI HUMAN MAP KINASE 10, MAPK 10, MAP KINASE P49 3F12, STRESS-ACTIVATED PROTEIN KINASE 1B, SAPK1B, STRESS-ACTIVATED PROTEIN KINASEJNK3, C-JUN N-TERMINAL KINASE 3 HUMAN
MAP KINASE 10, MAPK 10, MAP KINASE P49 3F12, STRES ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402