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GENERAL
TITLE
CRYSTAL STRUCTURE OF INTERLEUKIN-2 INDUCIBLE T-CELL KINASE ITK CATALYTIC DOMAIN WITH THIENOPYRAZOLYLINDOLE INHIBITOR 469
DATE LAST MODIFIED
8 Nov 2017
RELEASE
2 May 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.26
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2012.03.016
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08881 ITK, EMT, LYK SPODOPTERA FRUGIPERDA HUMAN INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCIBLE T CELLKINASE, KINASE EMT, T-CELL-SPECIFIC KINASE, TYROSINE-PROTEIN KINASELYK HUMAN
INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCI ...
Mutations
Q08881 ITK, EMT, LYK SPODOPTERA FRUGIPERDA HUMAN INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCIBLE T CELLKINASE, KINASE EMT, T-CELL-SPECIFIC KINASE, TYROSINE-PROTEIN KINASELYK HUMAN
INTERLEUKIN-2-INDUCIBLE T CELL KINASE, IL-2-INDUCI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402