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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF HUMAN VEGFR2 WITH A [1, 3]THIAZOLO[5,4-B]PYRIDINE DERIVATIVE
DATE LAST MODIFIED
7 Aug 2013
RELEASE
11 Apr 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.64
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM300126X
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P35968 KDR, FLK1, VEGFR2 SPODOPTERA FRUGIPERDA HUMAN VEGFR-2, FETAL LIVER KINASE 1, FLK-1, KINASE INSERT DOMAINRECEPTOR, KDR, PROTEIN-TYROSINE KINASE RECEPTOR FLK-1 HUMAN
VEGFR-2, FETAL LIVER KINASE 1, FLK-1, KINASE INSER ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402