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GENERAL
TITLE
STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE PYRIDINE INHIBITOR N-(1-(5-(TRIFLUOROMETHYL)(PYRIDIN-2-YL)) PIPERIDIN-4YL)-N-(4-(TRIFLUOROMETHYL)PHENYL)PYRIDIN-3-AMINE (EPL- BS967, UDD)
DATE LAST MODIFIED
6 Feb 2019
RELEASE
25 Sept 2013
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
74
PUBMED ID
DOI
10.1074/JBC.M113.497990

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q7Z1V1 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CYP51, TC14DM, CYTOCHROME P450 51
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402