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GENERAL
TITLE
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH TRI-SUBSTITUTED IMIDAZOLE INHIBITOR (4-(2-TERT-BUTYL- 4-(6-METHOXYNAPHTHALEN-2-YL)-1H-IMIDAZOL-5-YL)PYRIDIN-2-AMINE) AND L- METHIONINE-S-SULFOXIMINE PHOSPHATE
DATE LAST MODIFIED
15 May 2019
RELEASE
4 Apr 2012
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.26
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1021/JM201212H

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P9WN39 -- ESCHERICHIA COLI MYCOBACTERIUM TUBERCULOSIS
GLUTAMATE--AMMONIA LIGASE 1
Mutations
P9WN39 -- ESCHERICHIA COLI MYCOBACTERIUM TUBERCULOSIS
GLUTAMATE--AMMONIA LIGASE 1
Mutations
P9WN39 -- ESCHERICHIA COLI MYCOBACTERIUM TUBERCULOSIS
GLUTAMATE--AMMONIA LIGASE 1
Mutations
P9WN39 -- ESCHERICHIA COLI MYCOBACTERIUM TUBERCULOSIS
GLUTAMATE--AMMONIA LIGASE 1
Mutations
P9WN39 -- ESCHERICHIA COLI MYCOBACTERIUM TUBERCULOSIS
GLUTAMATE--AMMONIA LIGASE 1
Mutations
P9WN39 -- ESCHERICHIA COLI MYCOBACTERIUM TUBERCULOSIS
GLUTAMATE--AMMONIA LIGASE 1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402