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GENERAL
TITLE
HUMAN AURORA B KINASE IN COMPLEX WITH INCENP AND VX-680
DATE LAST MODIFIED
24 Jan 2018
RELEASE
11 Apr 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2.75
RESOLUTION RANGE LOW
69.41
PUBMED ID
DOI
10.1021/JM3008954
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q96GD4 -- ESCHERICHIA COLI HUMAN AURORA 1, AURORA B, AURORA- AND IPL1-LIKE MIDBODY-ASSOCIATEDPROTEIN 1, AIM-1, AURORA/IPL1-RELATED KINASE 2, ARK-2, AURORA-RELATEDKINASE 2, STK-1, SERINE/THREONINE 12 -PROTEIN KINASESERINE/THREONINE-PROTEIN KINASE 5, SERINE/THREONINE-PROTEIN KINASEAURORA-B HUMAN
AURORA 1, AURORA B, AURORA- AND IPL1-LIKE MIDBODY- ...
Mutations
Q9NQS7 -- ESCHERICHIA COLI HUMAN INCENP HUMAN
INCENP
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402