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GENERAL
TITLE
CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH AXITINIB (AG-013736) (N-METHYL-2-(3-((E)-2-PYRIDIN-2-YL- VINYL)-1H-INDAZOL-6-YLSULFANYL)-BENZAMIDE)
DATE LAST MODIFIED
8 May 2019
RELEASE
26 Sept 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1073/PNAS.1207759109
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P35968 -- SPODOPTERA FRUGIPERDA HUMAN
VEGFR-2, FETAL LIVER KINASE 1, FLK-1, KINASE INSER ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402