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GENERAL
TITLE
SELECTIVE SMALL MOLECULE INHIBITOR DISCOVERED BY CHEMOPROTEOMIC ASSAY PLATFORM REVEALS REGULATION OF TH17 CELL DIFFERENTIATION BY PI3KGAMMA
DATE LAST MODIFIED
11 Jul 2012
RELEASE
9 May 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
3.3
RESOLUTION RANGE LOW
109.76
PUBMED ID
DOI
10.1038/NCHEMBIO.957
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P48736 -- SPODOPTERA FRUGIPERDA HUMAN
PI3-KINASE SUBUNIT GAMMA, PI3K-GAMMA, PI3KGAMMA,PT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402