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GENERAL
TITLE
CRYSTAL STRUCTURE OF C-MET KINASE DOMAIN IN COMPLEX WITH 4-(3-((1H- PYRROLO(2,3-B)PYRIDIN-3-YL)METHYL)-(1,2,4)TRIAZOLO(4,3-B)(1,2,4) TRIAZIN-6-YL)BENZONITRILE
DATE LAST MODIFIED
8 May 2019
RELEASE
26 Sept 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
1.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM300967G
PDBe
4AOI
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P08581 | -- | SPODOPTERA FRUGIPERDA | HUMAN | HGF RECEPTOR, 2.7.10.1, HGF/SF RECEPTOR, PROTO-ONCOGENE C-MET, SCATTER FACTOR RECEPTOR, SF RECEPTOR, TYROSINE-PROTEIN KINASEMET | HUMAN | HGF RECEPTOR, 2.7.10.1, HGF/SF RECEPTOR, PROTO-ONC ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402