4AOJ logo

4AOJ

3D Structure View

Loading...

More Info

GENERAL
TITLE
HUMAN TRKA IN COMPLEX WITH THE INHIBITOR AZ-23
DATE LAST MODIFIED
8 May 2019
RELEASE
15 Aug 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
2.75
RESOLUTION RANGE LOW
42.06
PUBMED ID
DOI
10.1021/ML300074J
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P04629 -- SPODOPTERA FRUGIPERDA HUMAN NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1, TRK1-TRANSFORMING TYROSINE KINASE PROTEIN, TROPOMYOSIN-RELATED KINASE A,TYROSINE KINASE RECEPTOR, TYROSINE KINASE RECEPTOR A, TRK-A,GP140TRK, P140-TRKA, TRKA HUMAN
NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1, TRK1 ...
Mutations
P04629 -- SPODOPTERA FRUGIPERDA HUMAN NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1, TRK1-TRANSFORMING TYROSINE KINASE PROTEIN, TROPOMYOSIN-RELATED KINASE A,TYROSINE KINASE RECEPTOR, TYROSINE KINASE RECEPTOR A, TRK-A,GP140TRK, P140-TRKA, TRKA HUMAN
NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1, TRK1 ...
Mutations
P04629 -- SPODOPTERA FRUGIPERDA HUMAN NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1, TRK1-TRANSFORMING TYROSINE KINASE PROTEIN, TROPOMYOSIN-RELATED KINASE A,TYROSINE KINASE RECEPTOR, TYROSINE KINASE RECEPTOR A, TRK-A,GP140TRK, P140-TRKA, TRKA HUMAN
NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1, TRK1 ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402