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GENERAL
TITLE
STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH (1S)-2-AMINO-1-( 4-CHLOROPHENYL)-1-(4-(1H-PYRAZOL-4-YL)PHENYL)ETHAN-1-OL
DATE LAST MODIFIED
6 Feb 2013
RELEASE
25 Jul 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
54.6
PUBMED ID
DOI
10.1158/1078-0432.CCR-11-3313
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P17612 -- ESCHERICHIA COLI CATTLE PKA C-ALPHA CATTLE
PKA C-ALPHA
P61925 -- -- HUMAN PKI-ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR,MUSCLE/BRAIN ISOFORM HUMAN
PKI-ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402