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GENERAL
TITLE
STRUCTURE-BASED DESIGN OF ORALLY BIOAVAILABLE PYRROLOPYRIDINE INHIBITORS OF THE MITOTIC KINASE MPS1
DATE LAST MODIFIED
15 Jan 2014
RELEASE
4 Dec 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
58
PUBMED ID
DOI
10.1021/JM401395S

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P33981 -- ESCHERICHIA COLI HUMAN
2.7.12.1, PHOSPHOTYROSINE PICKED THREONINE-PROTEIN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402