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GENERAL
TITLE
STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991)
DATE LAST MODIFIED
8 May 2019
RELEASE
25 Dec 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
3.02
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1038/NCOMMS4017

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P54646 -- ESCHERICHIA COLI HUMAN AMPK SUBUNIT ALPHA-2, ACETYL-COA CARBOXYLASE KINASE, ACACAKINASE, HYDROXYMETHYLGLUTARYL-COA REDUCTASE KINASE, HMGCR KINASE HUMAN
AMPK SUBUNIT ALPHA-2, ACETYL-COA CARBOXYLASE KINAS ...
Mutations
Q9Y478 -- ESCHERICHIA COLI HUMAN AMPK SUBUNIT BETA-1, AMPKB HUMAN
AMPK SUBUNIT BETA-1, AMPKB
Mutations
P54646 -- ESCHERICHIA COLI HUMAN AMPK SUBUNIT ALPHA-2, ACETYL-COA CARBOXYLASE KINASE, ACACAKINASE, HYDROXYMETHYLGLUTARYL-COA REDUCTASE KINASE, HMGCR KINASE HUMAN
AMPK SUBUNIT ALPHA-2, ACETYL-COA CARBOXYLASE KINAS ...
Mutations
Q9Y478 -- ESCHERICHIA COLI HUMAN AMPK SUBUNIT BETA-1, AMPKB HUMAN
AMPK SUBUNIT BETA-1, AMPKB
Mutations
P54619 -- ESCHERICHIA COLI HUMAN AMPK GAMMA1, AMPK SUBUNIT GAMMA-1, AMPKG HUMAN
AMPK GAMMA1, AMPK SUBUNIT GAMMA-1, AMPKG
Mutations
P54619 -- ESCHERICHIA COLI HUMAN AMPK GAMMA1, AMPK SUBUNIT GAMMA-1, AMPKG HUMAN
AMPK GAMMA1, AMPK SUBUNIT GAMMA-1, AMPKG
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402