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4D9T

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GENERAL
TITLE
RSK2 C-TERMINAL KINASE DOMAIN WITH INHIBITOR (E)-METHYL 3-(4-AMINO-7- (3-HYDROXYPROPYL)-5-P-TOLYL-7H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-2- CYANOACRYLATE
DATE LAST MODIFIED
16 May 2012
RELEASE
25 Apr 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
36.6
PUBMED ID
DOI
10.1038/NCHEMBIO.925

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P51812 ISPK1, MAPKAPK1B, RPS6KA3, RSK2 ESCHERICHIA COLI HUMAN S6K-ALPHA-3, 90 KDA RIBOSOMAL PROTEIN S6 KINASE 3, P90-RSK3, P90RSK3, INSULIN-STIMULATED PROTEIN KINASE 1, ISPK-1, MAP KINASE-ACTIVATED PROTEIN KINASE 1B, MAPK-ACTIVATED PROTEIN KINASE 1B, MAPKAPKINASE 1B, MAPKAPK-1B, RIBOSOMAL S6 KINASE 2, RSK-2, PP90RSK2 HUMAN
S6K-ALPHA-3, 90 KDA RIBOSOMAL PROTEIN S6 KINASE 3, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402