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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN ANAPLASTIC LYMPHOMA KINASE IN COMPLEX WITH A PIPERIDINE-CARBOXAMIDE INHIBITOR
DATE LAST MODIFIED
15 Nov 2017
RELEASE
8 Feb 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.03
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM201565S
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9UM73 ALK SPODOPTERA FRUGIPERDA HUMAN ANAPLASTIC LYMPHOMA KINASE HUMAN
ANAPLASTIC LYMPHOMA KINASE
Mutations
Q9UM73 ALK SPODOPTERA FRUGIPERDA HUMAN ANAPLASTIC LYMPHOMA KINASE HUMAN
ANAPLASTIC LYMPHOMA KINASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402