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GENERAL
TITLE
QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH P218 AND NADPH
DATE LAST MODIFIED
15 Nov 2017
RELEASE
14 Nov 2012
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE, TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
19.9
PUBMED ID
DOI
10.1073/PNAS.1204556109
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
D9N170 DHFR-TS, V1/S ESCHERICHIA COLI PLASMODIUM FALCIPARUM --
D9N170 DHFR-TS, V1/S ESCHERICHIA COLI PLASMODIUM FALCIPARUM --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402