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GENERAL
TITLE
O-CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF FKBP52, RAPAMYCIN AND THE FRB FRAGMENT OF MTOR
DATE LAST MODIFIED
27 Mar 2013
RELEASE
6 Feb 2013
OBSOLETE
CLASSIFICATION
ISOMERASE/TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.8
RESOLUTION RANGE LOW
70.186
PUBMED ID
DOI
10.1128/MCB.00678-12

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q02790 FKBP4, FKBP52 ESCHERICHIA COLI HUMAN PPIASE FKBP4, 51 KDA FK506-BINDING PROTEIN, FKBP51, 52 KDAFK506-BINDING PROTEIN, 52 KDA FKBP, FKBP-52, 59 KDA IMMUNOPHILIN,P59, FK506-BINDING PROTEIN 4, FKBP-4, FKBP59, HSP-BINDINGIMMUNOPHILIN, HBI, IMMUNOPHILIN FKBP52, ROTAMASE, PEPTIDYL-PROLYLCIS-TRANS ISOMERASE FKBP4, N-TERMINALLY PROCESSED HUMAN
PPIASE FKBP4, 51 KDA FK506-BINDING PROTEIN, FKBP51 ...
Mutations
P42345 FRAP, FRAP1, FRAP2, MTOR, RAFT1, RAPT1 ESCHERICHIA COLI HUMAN FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIATEDPROTEIN 1, FKBP12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN, MAMMALIANTARGET OF RAPAMYCIN, MTOR, MECHANISTIC TARGET OF RAPAMYCIN, RAPAMYCINAND FKBP12 TARGET 1, RAPAMYCIN TARGET PROTEIN 1 HUMAN
FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402