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GENERAL
TITLE
STRUCTURE OF FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH NOVEL ALLOSTERIC INHIBITOR
DATE LAST MODIFIED
27 Mar 2013
RELEASE
25 Jul 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.6
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.EJMECH.2012.06.035
PDBe
4EBW
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| Q05397 | PTK2, FAK, FAK1 | SPODOPTERA FRUGIPERDA | HUMAN | FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, FRNK,PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 71, PPP1R71, PROTEIN-TYROSINE KINASE 2, P125FAK, PP125FAK | HUMAN | FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, F ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402