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GENERAL
TITLE
CRYSTAL STRUCTURE OF AUTOINHIBITED FORM OF AKT1 IN COMPLEX WITH N-(4- (5-(3-ACETAMIDOPHENYL)-2-(2-AMINOPYRIDIN-3-YL)-3H-IMIDAZO[4,5- B]PYRIDIN-3-YL)BENZYL)-3-FLUOROBENZAMIDE
DATE LAST MODIFIED
2 Jan 2013
RELEASE
23 May 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.19
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM300276X

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P31749 AKT1, PKB, RAC SPODOPTERA FRUGIPERDA HUMAN PROTEIN KINASE B, PKB, PROTEIN KINASE B ALPHA, PKB ALPHA,PROTO-ONCOGENE C-AKT, RAC-PK-ALPHA HUMAN
PROTEIN KINASE B, PKB, PROTEIN KINASE B ALPHA, PKB ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402