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GENERAL
TITLE
CRYSTAL STRUCTURE OF GSK6414 BOUND TO PERK (R587-R1092, DELETE A660- T867) AT 2.28 A RESOLUTION
DATE LAST MODIFIED
15 Nov 2017
RELEASE
8 Aug 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.28
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM300713S
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9NZJ5 EIF2AK3, PEK, PERK ESCHERICHIA COLI HUMAN PKR-LIKE ENDOPLASMIC RETICULUM KINASE, PERK, PANCREATICEIF2-ALPHA KINASE, HSPEK HUMAN
PKR-LIKE ENDOPLASMIC RETICULUM KINASE, PERK, PANCR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402