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GENERAL
TITLE
CRYSTAL STRUCTURE OF TS-DHFR FROM CRYPTOSPORIDIUM HOMINIS IN COMPLEX WITH NADPH, METHOTREXATE, FDUMP AND 4-((2-AMINO-6-METHYL-4-OXO-4,7- DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)THIO)-2-CHLOROPHENYL)-L- GLUTAMIC ACID
DATE LAST MODIFIED
15 Nov 2017
RELEASE
21 Aug 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE,OXIDOREDUCTASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
3.08
RESOLUTION RANGE LOW
48.12
PUBMED ID
DOI
10.1016/J.BMCL.2013.07.037
PDBe
4KY8
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| Q5CGA3 | CHRO.40506, TS-DHFR | ESCHERICHIA COLI | CRYPTOSPORIDIUM HOMINIS | -- | CRYPTOSPORIDIUM HOMINIS | -- | ||
| Q5CGA3 | CHRO.40506, TS-DHFR | ESCHERICHIA COLI | CRYPTOSPORIDIUM HOMINIS | -- | CRYPTOSPORIDIUM HOMINIS | -- | ||
| Q5CGA3 | CHRO.40506, TS-DHFR | ESCHERICHIA COLI | CRYPTOSPORIDIUM HOMINIS | -- | CRYPTOSPORIDIUM HOMINIS | -- | ||
| Q5CGA3 | CHRO.40506, TS-DHFR | ESCHERICHIA COLI | CRYPTOSPORIDIUM HOMINIS | -- | CRYPTOSPORIDIUM HOMINIS | -- | ||
| Q5CGA3 | CHRO.40506, TS-DHFR | ESCHERICHIA COLI | CRYPTOSPORIDIUM HOMINIS | -- | CRYPTOSPORIDIUM HOMINIS | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402