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GENERAL
TITLE
CRYSTAL STRUCTURE OF MEK1 KINASE BOUND TO GDC0973
DATE LAST MODIFIED
25 Sept 2013
RELEASE
7 Aug 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 62
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1038/NATURE12441

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q02750 MAP2K1, MEK1, PRKMK1 ESCHERICHIA COLI HUMAN MAP KINASE KINASE 1, MAPKK 1, MKK1, ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1, MEK 1 HUMAN
MAP KINASE KINASE 1, MAPKK 1, MKK1, ERK ACTIVATOR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402