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GENERAL
TITLE
HUMAN SRC KINASE BOUND TO KINASE INHIBITOR BOSUTINIB
DATE LAST MODIFIED
5 Feb 2014
RELEASE
4 Dec 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.1
RESOLUTION RANGE LOW
72.5
PUBMED ID
DOI
10.1038/NCHEMBIO.1404
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P12931 SRC, SRC1 ESCHERICHIA COLI HUMAN PROTO-ONCOGENE C-SRC, PP60C-SRC, P60-SRC HUMAN
PROTO-ONCOGENE C-SRC, PP60C-SRC, P60-SRC
Mutations
P12931 SRC, SRC1 ESCHERICHIA COLI HUMAN PROTO-ONCOGENE C-SRC, PP60C-SRC, P60-SRC HUMAN
PROTO-ONCOGENE C-SRC, PP60C-SRC, P60-SRC
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402