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GENERAL
TITLE
THE EFFECTS OF LYSINE 200 AND PHENYLALANINE 239 FARNESYL PYROPHOSPHATE SYNTHASE (FPPS) MUTATIONS ON THE CATALYTIC ACTIVITY, CRYSTAL STRUCTURE AND INHIBITION BY NITROGEN CONTAINING BISPHOSPHONATES
DATE LAST MODIFIED
31 Jan 2018
RELEASE
19 Nov 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
1.46
RESOLUTION RANGE LOW
37.09
PUBMED ID
-
DOI
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P14324 FDPS, FPS, KIAA1293 ESCHERICHIA COLI HUMAN
FPP SYNTHASE, FPS, (2E,6E)-FARNESYL DIPHOSPHATE SY ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402