3D Structure View
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GENERAL
TITLE
APPROACH FOR TARGETING RAS WITH SMALL MOLECULES THAT ACTIVATE SOS- MEDIATED NUCLEOTIDE EXCHANGE
DATE LAST MODIFIED
19 Mar 2014
RELEASE
12 Mar 2014
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 4 2 2
RESOLUTION RANGE HIGH
2.85
RESOLUTION RANGE LOW
42.984
PUBMED ID
DOI
10.1073/PNAS.1315798111
PDBe
4NYJ
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P01112 | HRAS, HRAS1 | ESCHERICHIA COLI | HUMAN | H-RAS-1, HA-RAS, TRANSFORMING PROTEIN P21, C-H-RAS ... | Mutations | |
| P01112 | HRAS, HRAS1 | ESCHERICHIA COLI | HUMAN | H-RAS-1, HA-RAS, TRANSFORMING PROTEIN P21, C-H-RAS ... | Mutations | |
| Q07889 | SOS1 | ESCHERICHIA COLI | HUMAN | SOS-1 | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402