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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH THE INHIBITOR TG-101348
DATE LAST MODIFIED
12 Feb 2020
RELEASE
26 Feb 2014
OBSOLETE
CLASSIFICATION
TRANSCRIPTION/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.65
RESOLUTION RANGE LOW
19.561
PUBMED ID
DOI
10.1038/NCHEMBIO.1471
PDBe
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LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60885 BRD4, HUNK1 ESCHERICHIA COLI HUMAN BRD4, PROTEIN HUNK1 HUMAN
BRD4, PROTEIN HUNK1
Mutations
O60885 BRD4, HUNK1 ESCHERICHIA COLI HUMAN BRD4, PROTEIN HUNK1 HUMAN
BRD4, PROTEIN HUNK1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402