4ORI

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4ORI_A

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GENERAL

TITLE

RAT DIHYDROOROTATE DEHYDROGENASE BOUND WITH DSM338 (N-[3,5-DIFLUORO-4- (TRIFLUOROMETHYL)PHENYL]-5-METHYL-2-(TRIFLUOROMETHYL)[1,2, 4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE)

DATE LAST MODIFIED

9 Jul 2014

RELEASE

4 Jun 2014

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.5

RESOLUTION RANGE LOW

PUBMED ID

24801997

DOI

10.1021/JM500481T

PDBe

4ORI

LIGANDS

1866014 , 350048 , 3435

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonyms	Actions
	Q63707	DHODH, DIHYDROOROTATE DEHYDROGENASE	ESCHERICHIA COLI	BROWN RAT,RAT,RATS	DHODEHASE, DIHYDROOROTATE OXIDASE	BROWN RAT,RAT,RATS	DHODEHASE, DIHYDROOROTATE OXIDASE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402