4ORM logo

4ORM

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM338 (N-[3,5-DIFLUORO-4- (TRIFLUOROMETHYL)PHENYL]-5-METHYL-2-(TRIFLUOROMETHYL)[1,2, 4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE)
DATE LAST MODIFIED
23 Aug 2017
RELEASE
4 Jun 2014
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 64
RESOLUTION RANGE HIGH
2.07
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM500481T

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08210 DIHYDROOROTATE DEHYDROGENASE, PFF0160C ESCHERICHIA COLI PLASMODIUM FALCIPARUM DHODEHASE, DIHYDROOROTATE OXIDASE PLASMODIUM FALCIPARUM
DHODEHASE, DIHYDROOROTATE OXIDASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402