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GENERAL
TITLE
CRYSTAL STRUCTURE OF PRK1 CATALYTIC DOMAIN IN COMPLEX WITH TOFACITINIB
DATE LAST MODIFIED
24 Jan 2018
RELEASE
27 Aug 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.93
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1371/JOURNAL.PONE.0103638
PDBe
4OTI
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| Q16512 | PKN1, PAK1, PKN, PRK1, PRKCL1 | TRICHOPLUSIA NI | HUMAN | PROTEASE-ACTIVATED KINASE 1, PAK-1, PROTEIN KINASE C-LIKE 1,PROTEIN KINASE C-LIKE PKN, PROTEIN KINASE PKN-ALPHA, PROTEIN-KINASEC-RELATED KINASE 1, SERINE-THREONINE PROTEIN KINASE N | HUMAN | PROTEASE-ACTIVATED KINASE 1, PAK-1, PROTEIN KINASE ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402