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GENERAL
TITLE
CRYSTAL STRUCTURE OF CORTISOL-BOUND GLUCOCORTICOID RECEPTOR LIGAND BINDING DOMAIN
DATE LAST MODIFIED
25 Dec 2019
RELEASE
16 Apr 2014
OBSOLETE
CLASSIFICATION
HORMONE RECEPTOR/HORMONE ACTIVATOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1038/CR.2014.52
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P04150 NR3C1, GRL ESCHERICHIA COLI K-12 HUMAN GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1 HUMAN
GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1
Mutations
Q15596 -- -- HUMAN NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2,HTIF2 HUMAN
NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,B ...
Mutations
P04150 NR3C1, GRL ESCHERICHIA COLI K-12 HUMAN GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1 HUMAN
GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1
Mutations
Q15596 -- -- HUMAN NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2,HTIF2 HUMAN
NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,B ...
Mutations
P04150 NR3C1, GRL ESCHERICHIA COLI K-12 HUMAN GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1 HUMAN
GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1
Mutations
Q15596 -- -- HUMAN NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2,HTIF2 HUMAN
NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,B ...
Mutations
P04150 NR3C1, GRL ESCHERICHIA COLI K-12 HUMAN GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1 HUMAN
GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1
Mutations
Q15596 -- -- HUMAN NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2,HTIF2 HUMAN
NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,B ...
Mutations
P04150 NR3C1, GRL ESCHERICHIA COLI K-12 HUMAN GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1 HUMAN
GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1
Mutations
Q15596 -- -- HUMAN NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2,HTIF2 HUMAN
NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,B ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402