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GENERAL
TITLE
STRUCTURE OF PARP1 CATALYTIC DOMAIN BOUND TO INHIBITOR BMN 673
DATE LAST MODIFIED
22 Nov 2017
RELEASE
24 Sept 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.35
RESOLUTION RANGE LOW
19.94
PUBMED ID
DOI
10.1107/S2053230X14015088

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P09874 PARP1, ADPRT, PPOL ESCHERICHIA COLI HUMAN PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1,NAD(+) ADP-RIBOSYLTRANSFERASE 1,ADPRT 1,POLY[ADP-RIBOSE] SYNTHASE 1 HUMAN
PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIK ...
Mutations
P09874 PARP1, ADPRT, PPOL ESCHERICHIA COLI HUMAN PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1,NAD(+) ADP-RIBOSYLTRANSFERASE 1,ADPRT 1,POLY[ADP-RIBOSE] SYNTHASE 1 HUMAN
PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIK ...
Mutations
P09874 PARP1, ADPRT, PPOL ESCHERICHIA COLI HUMAN PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1,NAD(+) ADP-RIBOSYLTRANSFERASE 1,ADPRT 1,POLY[ADP-RIBOSE] SYNTHASE 1 HUMAN
PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIK ...
Mutations
P09874 PARP1, ADPRT, PPOL ESCHERICHIA COLI HUMAN PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1,NAD(+) ADP-RIBOSYLTRANSFERASE 1,ADPRT 1,POLY[ADP-RIBOSE] SYNTHASE 1 HUMAN
PARP-1,ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIK ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402