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GENERAL
TITLE
THE STRUCTURE OF TRKA KINASE BOUND TO THE INHIBITOR N~4~-(4-MORPHOLIN- 4-YLPHENYL)-N~6~-(PYRIDIN-3-YLMETHYL)PYRIDO[3,2-D]PYRIMIDINE-4,6- DIAMINE
DATE LAST MODIFIED
25 Feb 2015
RELEASE
18 Jun 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 64
RESOLUTION RANGE HIGH
2.1
RESOLUTION RANGE LOW
56.67
PUBMED ID
DOI
10.1021/JM5006429

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P04629 NTRK1, MTC, TRK, TRKA SPODOPTERA FRUGIPERDA HUMAN
NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1,TRK1- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402