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GENERAL
TITLE
THE ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN D538G MUTANT IN COMPLEX WITH ESTRADIOL AND A GLUCOCORTICOID RECEPTOR-INTERACTING PROTEIN 1 NR BOX II PEPTIDE
DATE LAST MODIFIED
17 May 2017
RELEASE
8 Apr 2015
OBSOLETE
CLASSIFICATION
HORMONE/PEPTIDE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.89
RESOLUTION RANGE LOW
55.25
PUBMED ID
DOI
10.7554/ELIFE.12792
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P03372 ESR, ESR1, NR3A1 ESCHERICHIA COLI HUMAN ER, ER-ALPHA, ESTRADIOL RECEPTOR, NUCLEAR RECEPTOR SUBFAMILY3 GROUP A MEMBER 1 HUMAN
ER, ER-ALPHA, ESTRADIOL RECEPTOR, NUCLEAR RECEPTOR ...
Mutations
P03372 ESR, ESR1, NR3A1 ESCHERICHIA COLI HUMAN ER, ER-ALPHA, ESTRADIOL RECEPTOR, NUCLEAR RECEPTOR SUBFAMILY3 GROUP A MEMBER 1 HUMAN
ER, ER-ALPHA, ESTRADIOL RECEPTOR, NUCLEAR RECEPTOR ...
Mutations
Q15596 -- -- HUMAN NCOA-2, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75, BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2, HTIF2 HUMAN
NCOA-2, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75, ...
Mutations
Q15596 -- -- HUMAN NCOA-2, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75, BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2, HTIF2 HUMAN
NCOA-2, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402