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GENERAL
TITLE
CRYSTAL STRUCTURE OF TS-DHFR FROM CRYPTOSPORIDIUM HOMINIS IN COMPLEX WITH NADPH, FDUMP, METHOTREXATE AND 2-AMINO-4-OXO-4,7-DIHYDRO- PYRROLO[2,3-D]PYRIMIDINE-METHYL-PHENYL-L-GLUTAMIC ACID.
DATE LAST MODIFIED
22 Nov 2017
RELEASE
15 Oct 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
3.45
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2014.07.049

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q5CGA3 CHRO.40506, TS-DHFR ESCHERICHIA COLI CRYPTOSPORIDIUM HOMINIS -- CRYPTOSPORIDIUM HOMINIS --
Q5CGA3 CHRO.40506, TS-DHFR ESCHERICHIA COLI CRYPTOSPORIDIUM HOMINIS -- CRYPTOSPORIDIUM HOMINIS --
Q5CGA3 CHRO.40506, TS-DHFR ESCHERICHIA COLI CRYPTOSPORIDIUM HOMINIS -- CRYPTOSPORIDIUM HOMINIS --
Q5CGA3 CHRO.40506, TS-DHFR ESCHERICHIA COLI CRYPTOSPORIDIUM HOMINIS -- CRYPTOSPORIDIUM HOMINIS --
Q5CGA3 CHRO.40506, TS-DHFR ESCHERICHIA COLI CRYPTOSPORIDIUM HOMINIS -- CRYPTOSPORIDIUM HOMINIS --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402