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GENERAL
TITLE
THE ROLE OF THREONINE 201 AND TYROSINE 204 IN THE HUMAN FARNESYL PYROPHOSPHATE SYNTHASE CATALYTIC MECHANISM AND THE MODE OF INHIBITION BY THE NITROGEN-CONTAINING BISPHOSPHONATES
DATE LAST MODIFIED
31 Jan 2018
RELEASE
18 Mar 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
1.98
RESOLUTION RANGE LOW
25.02
PUBMED ID
-
DOI
--
PDBe
4Q23
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P14324 | FDPS, FPS, KIAA1293 | ESCHERICHIA COLI | HUMAN | FPP SYNTHASE, FPS, (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE,DIMETHYLALLYLTRANSTRANSFERASE, FARNESYL DIPHOSPHATE SYNTHASE,GERANYLTRANSTRANSFERASE | HUMAN | FPP SYNTHASE, FPS, (2E,6E)-FARNESYL DIPHOSPHATE SY ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402