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GENERAL
TITLE
THE SECOND SPHERE RESIDUE T263 IS IMPORTANT FOR FUNCTION AND ACTIVITY OF PTP1B THROUGH MODULATING WPD LOOP
DATE LAST MODIFIED
7 Feb 2018
RELEASE
11 Feb 2015
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BIOCEL.2014.10.004
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P18031 PTPN1, PTP1B ESCHERICHIA COLI HUMAN PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B HUMAN
PROTEIN-TYROSINE PHOSPHATASE 1B, PTP-1B
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402