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3D Structure View

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GENERAL
TITLE
TMK IN COMPLEX WITH COMPOUND 46, 2-(3-CHLOROPHENOXY)-3-FLUORO-4-{(1R)- 3-METHYL-1-[(3S)-3-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)- YL)PIPERIDIN-1-YL]BUTYL}BENZOIC ACID
DATE LAST MODIFIED
2 Jul 2014
RELEASE
11 Jun 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.62
RESOLUTION RANGE LOW
91.042
PUBMED ID
DOI
10.1021/JM500463C
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q6GJI9 SAR0483, TMK ESCHERICHIA COLI STAPHYLOCOCCUS AUREUS SUBSP. AUREUS
DTMP KINASE
Mutations
Q6GJI9 SAR0483, TMK ESCHERICHIA COLI STAPHYLOCOCCUS AUREUS SUBSP. AUREUS
DTMP KINASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402