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GENERAL
TITLE
CRYSTAL STRUCTURE OF INACTIVE HIV-1 PROTEASE VARIANT (I50V/A71V) IN COMPLEX WITH P1-P6 SUBSTRATE VARIANT (L449F)
DATE LAST MODIFIED
3 Dec 2014
RELEASE
29 Oct 2014
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1073/PNAS.1414063111
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03369 GAG-POL ESCHERICHIA COLI HIV-1
RETROPEPSIN
Mutations
P03369 GAG-POL ESCHERICHIA COLI HIV-1
RETROPEPSIN
Mutations
P03369 GAG-POL ESCHERICHIA COLI HIV-1
RETROPEPSIN
Mutations
P03369 GAG-POL ESCHERICHIA COLI HIV-1
RETROPEPSIN
Mutations
P03349 -- -- HUMAN IMMUNODEFICIENCY VIRUS 1
P6*
Mutations
P03349 -- -- HUMAN IMMUNODEFICIENCY VIRUS 1
P6*
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402