4QTE logo

4QTE

3D Structure View

Loading...

More Info

GENERAL
TITLE
STRUCTURE OF ERK2 IN COMPLEX WITH VTX-11E, 4-{2-[(2-CHLORO-4- FLUOROPHENYL)AMINO]-5-METHYLPYRIMIDIN-4-YL}-N-[(1S)-1-(3- CHLOROPHENYL)-2-HYDROXYETHYL]-1H-PYRROLE-2-CARBOXAMIDE
DATE LAST MODIFIED
24 Sept 2014
RELEASE
23 Jul 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
1.5
RESOLUTION RANGE LOW
83.77
PUBMED ID
DOI
10.1038/NCHEMBIO.1629

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P28482 ERK2, MAPK1, PRKM1, PRKM2 ESCHERICHIA COLI HUMAN
MAP KINASE 1, MAPK 1, ERT1, EXTRACELLULAR SIGNAL-R ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402