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GENERAL
TITLE
AZA-ACYCLIC NUCLEOSIDE PHOSPHONATES CONTAINING A SECOND PHOSPHONATE GROUP AS INHIBITORS OF THE HUMAN, PLASMODIUM FALCIPARUM AND VIVAX 6- OXOPURINE PHOSPHORIBOSYLTRANSFERASES AND THEIR PRO-DRUGS AS ANTIMALARIAL AGENTS
DATE LAST MODIFIED
23 Dec 2015
RELEASE
7 Jan 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.26
RESOLUTION RANGE LOW
41.53
PUBMED ID
DOI
10.1021/JM501416T
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P32321 | HPRT1, HPRT | ESCHERICHIA COLI | HUMAN | HGPRT, HGPRTASE | ||
| P32321 | HPRT1, HPRT | ESCHERICHIA COLI | HUMAN | HGPRT, HGPRTASE | ||
| P32321 | HPRT1, HPRT | ESCHERICHIA COLI | HUMAN | HGPRT, HGPRTASE | ||
| P32321 | HPRT1, HPRT | ESCHERICHIA COLI | HUMAN | HGPRT, HGPRTASE |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402