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GENERAL
TITLE
AZA-ACYCLIC NUCLEOSIDE PHOSPHONATES CONTAINING A SECOND PHOSPHONATE GROUP AS INHIBITORS OF THE HUMAN, PLASMODIUM FALCIPARUM AND VIVAX 6- OXOPURINE PHOSPHORIBOSYLTRANSFERASES AND THEIR PRO-DRUGS AS ANTIMALARIAL AGENTS
DATE LAST MODIFIED
23 Dec 2015
RELEASE
7 Jan 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.26
RESOLUTION RANGE LOW
41.53
PUBMED ID
DOI
10.1021/JM501416T
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00492 HPRT1, HPRT ESCHERICHIA COLI HUMAN
HGPRT, HGPRTASE
Mutations
P00492 HPRT1, HPRT ESCHERICHIA COLI HUMAN
HGPRT, HGPRTASE
Mutations
P00492 HPRT1, HPRT ESCHERICHIA COLI HUMAN
HGPRT, HGPRTASE
Mutations
P00492 HPRT1, HPRT ESCHERICHIA COLI HUMAN
HGPRT, HGPRTASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402