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4RV6

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GENERAL
TITLE
HUMAN ARTD1 (PARP1) CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR RUCAPARIB
DATE LAST MODIFIED
5 Sept 2018
RELEASE
9 Dec 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 2 1
RESOLUTION RANGE HIGH
3.19
RESOLUTION RANGE LOW
47.95
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.6B00990

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P09874 ADPRT, PARP1, PPOL ESCHERICHIA COLI HUMAN PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1, NAD(+) ADP-RIBOSYLTRANSFERASE 1, ADPRT 1, POLY[ADP-RIBOSE]SYNTHASE 1 HUMAN
PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LI ...
Mutations
P09874 ADPRT, PARP1, PPOL ESCHERICHIA COLI HUMAN PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1, NAD(+) ADP-RIBOSYLTRANSFERASE 1, ADPRT 1, POLY[ADP-RIBOSE]SYNTHASE 1 HUMAN
PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LI ...
Mutations
P09874 ADPRT, PARP1, PPOL ESCHERICHIA COLI HUMAN PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1, NAD(+) ADP-RIBOSYLTRANSFERASE 1, ADPRT 1, POLY[ADP-RIBOSE]SYNTHASE 1 HUMAN
PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LI ...
Mutations
P09874 ADPRT, PARP1, PPOL ESCHERICHIA COLI HUMAN PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LIKE 1,ARTD1, NAD(+) ADP-RIBOSYLTRANSFERASE 1, ADPRT 1, POLY[ADP-RIBOSE]SYNTHASE 1 HUMAN
PARP-1, ADP-RIBOSYLTRANSFERASE DIPHTHERIA TOXIN-LI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402