4RWI logo

4RWI

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF V561M FGFR1 GATEKEEPER MUTATION (C488A, C584S, V561M), APO
DATE LAST MODIFIED
22 Nov 2017
RELEASE
15 Apr 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.29
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACSCHEMBIO.5B00014
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P11362 BFGFR, CEK, FGFBR, FGFR1, FLG, FLT2, HBGFR ESCHERICHIA COLI HUMAN
FGFR-1, BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1, ...
Mutations
P11362 BFGFR, CEK, FGFBR, FGFR1, FLG, FLT2, HBGFR ESCHERICHIA COLI HUMAN
FGFR-1, BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402