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GENERAL
TITLE
CRYSTAL STRUCTURE OF FGFR1 (C488A, C584C) IN COMPLEX WITH 6-(7-((1- AMINOCYCLOPROPYL) METHOXY)-6-METHOXYQUINOLIN-4-YLOXY)-N-METHYL-1- NAPHTHAMIDE (E3810)
DATE LAST MODIFIED
22 Nov 2017
RELEASE
15 Apr 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.19
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACSCHEMBIO.5B00014
PDBe
4RWL
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q709F0 | BFGFR, CEK, FGFBR, FGFR1, FLG, FLT2, HBGFR | ESCHERICHIA COLI | HUMAN | FGFR-1, BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1, ... | ||
| Q709F0 | BFGFR, CEK, FGFBR, FGFR1, FLG, FLT2, HBGFR | ESCHERICHIA COLI | HUMAN | FGFR-1, BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1, ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402