4TW9

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4TW9_1

Chain 4TW9_A

Chain 4TW9_B

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GENERAL

TITLE

DIFLUORO-DIOXOLO-BENZOIMIDAZOL-BENZAMIDES AS POTENT INHIBITORS OF CK1DELTA AND EPSILON WITH NANOMOLAR INHIBITORY ACTIVITY ON CANCER CELL PROLIFERATION

DATE LAST MODIFIED

29 Jul 2020

RELEASE

30 Jul 2014

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.4

RESOLUTION RANGE LOW

19.86

PUBMED ID

25191940

DOI

10.1021/JM500600B

PDBe

LIGANDS

679408 , 2733538 , , 2694652 , 2730972

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P62314	CSNK1D, HCKID	ESCHERICHIA COLI	HUMAN	CKID,TAU-PROTEIN KINASE CSNK1D, CASEIN KINASE 1 DE ...
	P62306	CSNK1D, HCKID	ESCHERICHIA COLI	HUMAN	CKID,TAU-PROTEIN KINASE CSNK1D, CASEIN KINASE 1 DE ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402