4TWP

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4TWP_A

Chain 4TWP_B

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GENERAL

TITLE

THE CRYSTAL STRUCTURE OF HUMAN ABL1 T315I GATEKEEPER MUTANT KINASE DOMAIN IN COMPLEX WITH AXITINIB

DATE LAST MODIFIED

22 Nov 2017

RELEASE

11 Feb 2015

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 2 21 21

RESOLUTION RANGE HIGH

2.4

RESOLUTION RANGE LOW

85.957

PUBMED ID

DOI

10.1038/NATURE14119

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P17210	ABL1, ABL, JTK7	SPODOPTERA FRUGIPERDA	HUMAN	ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1,A ...
	P17210	ABL1, ABL, JTK7	SPODOPTERA FRUGIPERDA	HUMAN	ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1,A ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402