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4TY6

3D Structure View

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GENERAL
TITLE
FACTOR XIA IN COMPLEX WITH THE INHIBITOR 4-{2-[(1S)-1-({[TRANS-4- (AMINOMETHYL)CYCLOHEXYL]CARBONYL}AMINO)-2-PHENYLETHYL]-1H-IMIDAZOL-4- YL}BENZAMIDE
DATE LAST MODIFIED
22 Nov 2017
RELEASE
3 Dec 2014
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
1.85
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM5010607

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03951 F11 ESCHERICHIA COLI HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
P03951 F11 ESCHERICHIA COLI HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402