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GENERAL
TITLE
SAR156497 AN EXQUISITELY SELECTIVE INHIBITOR OF AURORA KINASES
DATE LAST MODIFIED
21 Jan 2015
RELEASE
19 Nov 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
39.84
PUBMED ID
DOI
10.1021/JM501326K
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O14965 -- ESCHERICHIA COLI HUMAN
AURORA 2, AURORA/IPL1-RELATED KINASE 1, ARK-1,AURO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402