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GENERAL
TITLE
STRUCTURE OF HS/ACPRC2 IN COMPLEX WITH 5,8-DICHLORO-2-[(4-METHOXY-6- METHYL-2-OXO-1,2-DIHYDROPYRIDIN-3-YL)METHYL]-7-[(R)-METHOXY(OXETAN-3- YL)METHYL]-3,4-DIHYDROISOQUINOLIN-1(2H)-ONE
DATE LAST MODIFIED
21 Feb 2018
RELEASE
27 Dec 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.81
RESOLUTION RANGE LOW
148.01
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.7B01375
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
G1KPH4 EZH2 SPODOPTERA FRUGIPERDA GREEN ANOLE --
G1KPH4 EZH2 SPODOPTERA FRUGIPERDA GREEN ANOLE --
O75530 EED SPODOPTERA FRUGIPERDA HUMAN
HEED,EMBRYONIC ECTODERM DEVELOPMENT PROTEIN,WD PRO ...
Mutations
O75530 EED SPODOPTERA FRUGIPERDA HUMAN
HEED,EMBRYONIC ECTODERM DEVELOPMENT PROTEIN,WD PRO ...
Mutations
Q15022 SUZ12, CHET9, JJAZ1, KIAA0160 SPODOPTERA FRUGIPERDA HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
Mutations
Q15022 SUZ12, CHET9, JJAZ1, KIAA0160 SPODOPTERA FRUGIPERDA HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402