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GENERAL
TITLE
A SINGLE DIASTEREOMER OF A MACROLACTAM CORE BINDS SPECIFICALLY TO MYELOID CELL LEUKEMIA 1 (MCL1)
DATE LAST MODIFIED
29 Jul 2020
RELEASE
19 Nov 2014
OBSOLETE
CLASSIFICATION
APOPTOSIS/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
1.85
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ML500388Q
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P0AEY0 MALE, Z5632, ECS5017, MCL1, BCL2L3 ESCHERICHIA COLI HUMAN
MBP,MMBP,MALTODEXTRIN-BINDING PROTEIN,BCL-2-LIKE P ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402